Synovetin OA® targets arthritis inflammation at its source.
Designed to deliver microscopic medical particles (called tin-117m), Synovetin OA treats inflammation inside the joint, eliminating the harmful cells that cause arthritis to develop and get worse over time. It’s similar to the medical radiotherapy that is routinely used to safely and effectively treat numerous medical conditions in people.
Completely different from other dog arthritis treatments.
Other dog arthritis treatments work to mask pain symptoms but can’t address the cause of the disease itself the way Synovetin OA can. And, because Synovetin OA works only inside the arthritic joint, it does not spread throughout the body like other treatments do, which can cause side effects.

Synovetin OA provides safe, effective, proven relief.
Safe
No systemic
side-effects4
Convenient
Just 1 fast, simple
minimally-invasive treatment
Long-lasting Results
Up to 1 full year
of pain relief2,3

Proven effective, very long-lasting, and safe in clinical studies.1
The active ingredient in Synovetin OA is only present in the body for a few weeks but the effect on inflammation and the resulting joint pain is very long-lasting—up to 1 full year, depending on the severity of arthritis. Plus, extensive safety studies and real-world use of Synovetin OA showed it does not cause systemic adverse effects and is safe for your dog, other pets, and your family.
How Synovetin OA® Works

Just 1 simple treatment has been proven to relieve OA pain for up to 1 full year.2,3

Quick Turnaround!
“He was less than a year old when he started limping. It was heartbreaking. But with Synovetin OA, the turnaround was really quick. He was moving around, fetching and playing. I couldn’t believe how soon it was that he was feeling better.”
Heather Hopkins
Pet parent of Mykonos, 7-year-old German Shepherd
Synoventin OA
He’s doing circles around us
“When our doctor contacted us about Synovetin OA, we did a little investigation and it was like a “eureka moment.” Now, we take him out on our mile-long walks and he does circles around us. We’re back to having our best friend with us again.”
Dr. Nick DeWees
Pet Parent of Reznor, 12-year-old yellow Labrador Retriever
An awesome opportunity!
“It’s awful not to see your dog do those things that enhance your animal bond. This is such an awesome opportunity to have 1 injection that lasts up to a year to provide pain relief.”
Dr. Anne Culp
Onion River Animal Hospital
Synoventin OA
Synovetin OA has opened up another pain management option
“Synovetin OA gives dog owners an option that frees them from pain medications.”
Dr. Jennifer Fletcher-Eckenrode
Animal Hospital of Dauphin County
Targeting the source of the pain.
“It’s another tool in our tool belt that isn’t just blanketing the problem but is really targeting the source of pain and inflammation. This is where we can have the most profound effect on the course of the disease.”
David Dycus
DVM, MS, DACVS, CCRP
Director/Chief of Orthopedic Surgery

Synoventin OA
One of the safest treatment options.
“Synovetin OA has an exceptionally low risk of complications. So, in my mind, Synovetin OA is one of the safest treatment options that we have for elbow arthritis at this point in time.”
Caleb Hudson
Sports Medicine, Surgery & Orthopedics
Synovetin OA Clinical Investigator




In the joint fluid of an arthritic joint, inflammatory cells drive pain and progression of the disease. Inflammation is the source of pain–where it begins. The inflammatory cells in inflamed joints produce substances that cause even more inflammation and damage to the joint. This is called “the vicious cycle of inflammation” and if left untreated, it causes ongoing inflammation, pain, and damage to the cartilage that lines the joint.
The effectiveness of Synovetin OA was studied in multiple clinical trials of dogs with elbow arthritis. Researchers evaluated Synovetin OA in its ability to relieve arthritis pain in dogs, such as lameness (limping), level of activity, and signs of pain during the year-long studies.
In most cases, you should begin to see improvement in your dog’s mobility within a few weeks, depending on the severity of arthritis. Some dog owners see results almost immediately, while in other instances of severe arthritis, it can be up to 2 months. This improvement should continue over time as Synovetin OA works inside the joint to reduce inflammation.
Synovetin OA is a treatment that consists of microscopic particles of the unique isotope tin-117m. These targeted particles emit a form of mild radiation energy that inactivates the harmful cells causing inflammation within the joint and the tissues surrounding the joint (called the synovium) and that drive the loss of cartilage. This activity helps to restore joint health and provides very long lasting pain relief without the systemic side effects that can commonly occur with daily and monthly dog arthritis drugs.
Synovetin OA is administered directly into the arthritic joint where it remains and works locally to eliminate inflammation–the driver of pain and progression of arthritis. It does not travel through the dog’s body and therefore causes no systemic side effects. This is in contrast to pain drugs such as daily NSAIDs or monthly injections, which are metabolized systemically in the dog’s body and have known, significant side effects.
